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Symbol
Name
ID
Rhoh
ras homolog family member H
MGI:1921984
Phenotype annotations related to immune system
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations
Human Phenotypes
Abnormality of the immune system
Seborrheic dermatitis
Pustule
Recurrent skin infections
Disease(s) Associated with RHOH
epidermodysplasia verruciformis

Mouse Phenotypes
immune system phenotype
decreased T cell apoptosis
abnormal T cell proliferation
decreased T cell proliferation
increased T cell proliferation
decreased mast cell degranulation
thymus hypoplasia
abnormal double-negative T cell morphology
increased double-negative T cell number
decreased double-positive T cell number
arrested T cell differentiation
abnormal lymphocyte cell number
increased NK cell number
decreased CD4-positive, alpha-beta T cell number
decreased CD8-positive, alpha-beta T cell number
increased NK T cell number
increased gamma-delta T cell number
decreased T cell number
decreased single-positive T cell number
increased T cell number
spleen hypoplasia
abnormal splenic cell ratio
abnormal mast cell physiology
abnormal immune system organ morphology
decreased susceptibility to type I hypersensitivity reaction
Availability Mouse Genotype
Rhohtm1Brak/Rhohtm1Brak
Rhohtm1Daw/Rhohtm1Daw
Rhohtm1Hasu/Rhohtm1Hasu *

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory